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Some people have lost a significant amount of weight, while others mention issues such as nausea or tiredness in the first few weeks

That said, signs or symptoms that you may be low in vitamin B12 include: fatigue pale skin headaches symptoms of depression stomach issues difficulty focusing or concentrating pain or inflammation in the mouth or on the tongue burning or pins and needles feeling in your hands or feet muscle cramps vision changes Learn more: Signs and symptoms of B12 deficiency

Store them in their original packaging when possible

Ongoing follow-up appointments allow providers to review progress, answer questions, and make adjustments when clinically appropriate

However, human intestinal absorption, first-pass metabolism, and systemic bioavailability have not been measured